inmoose.deseq2.DESeqDataSet

class inmoose.deseq2.DESeqDataSet.DESeqDataSet(countData, clinicalData=None, design=None, ignoreRank=False)

DESeqDataSet extends AnnData class to store observations (samples) of variables/features in the rows of a matrix. AnnData also offers a convenient way to store observation-wise (per row) and feature-wise (per column) data.

Methods

__init__(countData[, clinicalData, design, ...])

DESeqDataSet constructor

counts([normalized, replaced])

Accessor for the counts of a DESeqDataSet, which are stored as a matrix of non-negative integer, with one row per observation and one column per feature.

estimateDispersions([fitType, maxit, useCR, ...])

Estimate the dispersions for a DESeqDataSet

estimateSizeFactors([type_, locfunc, ...])

Estimate the size factors of a DESeqDataSet

results([contrast, name, lfcThreshold, ...])

Extract results from a DESeq() analysis

setDispFunction(value[, estimateVar])

Setter for the DESeqDataSet.dispersionFunction property

Attributes

design

design matrix

dispersions

accessor for the dispersions

dispersionFunction

dispersion function

dispersions

accessor for the dispersions

normalizationFactors

accessor for the normalization factors

sizeFactors

accessor for the size factors